Ras functional proximity proteomics establishes mTORC2 as new direct ras effector

Although oncogenic mutations in the three major Ras isoforms, KRAS, HRAS and NRAS, are present in nearly a third of human cancers, therapeutic targeting of Ras remains a challenge due to its structure and complex regulation. However, an in-depth examination of the protein interactome of oncogenic Ra...

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Detalles Bibliográficos
Autores principales: Kovalski, Joanna R., Shanderson, Ronald L., Khavari, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718260/
https://www.ncbi.nlm.nih.gov/pubmed/31497244
http://dx.doi.org/10.18632/oncotarget.27025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718260/
https://www.ncbi.nlm.nih.gov/pubmed/31497244
http://dx.doi.org/10.18632/oncotarget.27025

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