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Increased expression of cathepsin D is required for L1-mediated colon cancer progression
Hyperactivation of Wnt/β-catenin target genes is considered a key step in human colorectal cancer (CRC) development. We previously identified the immunoglobulin-like cell adhesion receptor L1 as a target gene of β-catenin/TCF transactivation that is localized at the invasive edge of CRC tissue. Usin...
Autores principales: | Basu, Sayon, Cheriyamundath, Sanith, Gavert, Nancy, Brabletz, Thomas, Haase, Gal, Ben-Ze’ev, Avri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718269/ https://www.ncbi.nlm.nih.gov/pubmed/31497251 http://dx.doi.org/10.18632/oncotarget.27155 |
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