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Enhanced monocyte recruitment and delayed alternative macrophage polarization accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice

Activation of the innate immune response following myocardial infarction (MI) is essential for infarct repair. Preclinical models of MI commonly use C57BL/6 mice, which have a type 1‐dominant immune response, whereas other mouse strains such as BALB/c mice have a type 2‐dominant immune response. We...

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Detalles Bibliográficos
Autores principales: Toor, I. S., Rückerl, D., Mair, I., Thomson, A., Rossi, A. G., Newby, D. E., Allen, J. E., Gray, G. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718279/
https://www.ncbi.nlm.nih.gov/pubmed/31119724
http://dx.doi.org/10.1111/cei.13330