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Combined hydrophilic interaction liquid chromatography-scanning field asymmetric waveform ion mobility spectrometry-time-of-flight mass spectrometry for untargeted metabolomics

Untargeted metabolite profiling of biological samples is a challenge for analytical science due to the high degree of complexity of biofluids. Isobaric species may also not be resolved using mass spectrometry alone. As a result of these factors, many potential biomarkers may not be detected or are m...

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Detalles Bibliográficos
Autores principales: Szykuła, Katarzyna M., Meurs, Joris, Turner, Matthew A., Creaser, Colin S., Reynolds, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718375/
https://www.ncbi.nlm.nih.gov/pubmed/31011786
http://dx.doi.org/10.1007/s00216-019-01790-6