A rapid and quantitative technique for assessing IgG monomeric purity, calibrated with the NISTmAb reference material

The fraction of intact monomer in a sample (moles/moles), the monomeric purity, is measured as a quality control in therapeutic monoclonal antibodies but is often unknown in research samples and remains a major source of variation in quantitative antibody-based techniques such as immunoassay develop...

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Detalles Bibliográficos
Autores principales: Reader, Peter P., Olkhov, Rouslan V., Reeksting, Shaun, Lubben, Anneke, Hyde, Christopher J., Shaw, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718376/
https://www.ncbi.nlm.nih.gov/pubmed/31375854
http://dx.doi.org/10.1007/s00216-019-02029-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718376/
https://www.ncbi.nlm.nih.gov/pubmed/31375854
http://dx.doi.org/10.1007/s00216-019-02029-0

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