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A rapid and quantitative technique for assessing IgG monomeric purity, calibrated with the NISTmAb reference material
The fraction of intact monomer in a sample (moles/moles), the monomeric purity, is measured as a quality control in therapeutic monoclonal antibodies but is often unknown in research samples and remains a major source of variation in quantitative antibody-based techniques such as immunoassay develop...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718376/ https://www.ncbi.nlm.nih.gov/pubmed/31375854 http://dx.doi.org/10.1007/s00216-019-02029-0 |