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TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex

Cerebral cortex expansion is a hallmark of mammalian brain evolution; yet, how increased neurogenesis is coordinated with structural and functional development remains largely unclear. The T-box protein TBR2/EOMES is preferentially enriched in intermediate progenitors and supports cortical neurogene...

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Detalles Bibliográficos
Autores principales: Lv, Xiaohui, Ren, Si-Qiang, Zhang, Xin-Jun, Shen, Zhongfu, Ghosh, Tanay, Xianyu, Anjin, Gao, Peng, Li, Zhizhong, Lin, Susan, Yu, Yang, Zhang, Qiangqiang, Groszer, Matthias, Shi, Song-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718393/
https://www.ncbi.nlm.nih.gov/pubmed/31477701
http://dx.doi.org/10.1038/s41467-019-11854-x