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ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER–plasma membrane junctions

Specific molecular interactions that underpin the switch between ER stress-triggered autophagy-mediated cellular repair and cellular death by apoptosis are not characterized. This study reports the unexpected interaction elicited by ER stress between the plasma membrane (PM)-localized apoptosis effe...

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Detalles Bibliográficos
Autores principales: McDonnell, Samantha J., Spiller, David G., White, Michael R. H., Prior, Ian A., Paraoan, Luminita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718399/
https://www.ncbi.nlm.nih.gov/pubmed/31508245
http://dx.doi.org/10.1038/s41420-019-0212-4