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Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome

Natural killer (NK) cells are critical to both innate and adaptive immunity. However, the development and heterogeneity of human NK cells are yet to be fully defined. Using single-cell RNA-sequencing technology, here we identify distinct NK populations in human bone marrow and blood, including one p...

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Detalles Bibliográficos
Autores principales: Yang, Chao, Siebert, Jason R., Burns, Robert, Gerbec, Zachary J., Bonacci, Benedetta, Rymaszewski, Amy, Rau, Mary, Riese, Matthew J., Rao, Sridhar, Carlson, Karen-Sue, Routes, John M., Verbsky, James W., Thakar, Monica S., Malarkannan, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718415/
https://www.ncbi.nlm.nih.gov/pubmed/31477722
http://dx.doi.org/10.1038/s41467-019-11947-7