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Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome
Natural killer (NK) cells are critical to both innate and adaptive immunity. However, the development and heterogeneity of human NK cells are yet to be fully defined. Using single-cell RNA-sequencing technology, here we identify distinct NK populations in human bone marrow and blood, including one p...
Autores principales: | Yang, Chao, Siebert, Jason R., Burns, Robert, Gerbec, Zachary J., Bonacci, Benedetta, Rymaszewski, Amy, Rau, Mary, Riese, Matthew J., Rao, Sridhar, Carlson, Karen-Sue, Routes, John M., Verbsky, James W., Thakar, Monica S., Malarkannan, Subramaniam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718415/ https://www.ncbi.nlm.nih.gov/pubmed/31477722 http://dx.doi.org/10.1038/s41467-019-11947-7 |
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