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NCAM1/FGF module serves as a putative pleuropulmonary blastoma therapeutic target

Pleuropulmonary blastoma (PPB) is a rare pediatric lung neoplasm that recapitulates developmental pathways of early embryonic lungs. As lung development proceeds with highly regulated mesenchymal-epithelial interactions, a DICER1 mutation in PPB generates a faulty lung differentiation program with r...

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Detalles Bibliográficos
Autores principales: Shukrun, Rachel, Golan, Hana, Caspi, Revital, Pode-Shakked, Naomi, Pleniceanu, Oren, Vax, Einav, Bar-Lev, Dekel D., Pri-Chen, Sara, Jacob-Hirsch, Jasmine, Schiby, Ginette, Harari-Steinberg, Orit, Mark-Danieli, Michal, Dekel, Benjamin, Toren, Amos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718423/
https://www.ncbi.nlm.nih.gov/pubmed/31477684
http://dx.doi.org/10.1038/s41389-019-0156-9