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HSP60-regulated Mitochondrial Proteostasis and Protein Translation Promote Tumor Growth of Ovarian Cancer

Ovarian cancer (OC) is the most lethal gynecological carcinoma due to the lack of diagnostic markers and effective drug targets. Discovery of new therapeutic targets in OC to improve the treatment outcome is urgently needed. We performed proteomic analysis of OC specimens and the paired normal tissu...

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Detalles Bibliográficos
Autores principales: Guo, Jianying, Li, Xiao, Zhang, Wenhao, Chen, Yuling, Zhu, Songbiao, Chen, Liang, Xu, Renhua, Lv, Yang, Wu, Di, Guo, Mingzhou, Liu, Xiaohui, Lu, Weiguo, Deng, Haiteng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718431/
https://www.ncbi.nlm.nih.gov/pubmed/31477750
http://dx.doi.org/10.1038/s41598-019-48992-7