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11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γ

Oxysterols previously were considered intermediates of bile acid and steroid hormone biosynthetic pathways. However, recent research has emphasized the roles of oxysterols in essential physiologic processes and in various diseases. Despite these discoveries, the metabolic pathways leading to the dif...

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Detalles Bibliográficos
Autores principales: Beck, Katharina R., Inderbinen, Silvia G., Kanagaratnam, Sharavan, Kratschmar, Denise V., Jetten, Anton M., Yamaguchi, Hideaki, Odermatt, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718442/
https://www.ncbi.nlm.nih.gov/pubmed/31273032
http://dx.doi.org/10.1194/jlr.M092908