Magnesium Restores Activity to Peripheral Blood Cells in a Patient With Functionally Impaired Interleukin-2-Inducible T Cell Kinase

Interleukin-2-inducible T cell kinase (ITK) is critical for T cell signaling and cytotoxicity, and control of Epstein-Barr virus (EBV). We identified a patient with a novel homozygous missense mutation (D540N) in a highly conserved residue in the kinase domain of ITK who presented with EBV-positive...

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Detalles Bibliográficos
Autores principales: Howe, Matthew K., Dowdell, Kennichi, Roy, Amitava, Niemela, Julie E., Wilson, Wyndham, McElwee, Joshua J., Hughes, Jason D., Cohen, Jeffrey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718476/
https://www.ncbi.nlm.nih.gov/pubmed/31507602
http://dx.doi.org/10.3389/fimmu.2019.02000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718476/
https://www.ncbi.nlm.nih.gov/pubmed/31507602
http://dx.doi.org/10.3389/fimmu.2019.02000

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