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Activation of Human NK Cells by Bordetella pertussis Requires Inflammasome Activation in Macrophages

Pertussis is a highly contagious respiratory infection caused by the bacterium Bordetella pertussis. Humans are the only known natural reservoir of B. pertussis. In mice, macrophages and NK cells have a key role in confining B. pertussis to the respiratory tract. However, the mechanisms underlying t...

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Detalles Bibliográficos
Autores principales: Kroes, Michiel M., Mariman, Rob, Hijdra, Daniëlle, Hamstra, Hendrik-Jan, van Boxtel, Karlijn J. W. M., van Putten, Jos P. M., de Wit, Jelle, Pinelli, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718514/
https://www.ncbi.nlm.nih.gov/pubmed/31507615
http://dx.doi.org/10.3389/fimmu.2019.02030