Peroxisome proliferator‐activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging

Age‐related impairment of muscle function severely affects the health of an increasing elderly population. While causality and the underlying mechanisms remain poorly understood, exercise is an efficient intervention to blunt these aging effects. We thus investigated the role of the peroxisome proli...

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Detalles Bibliográficos
Autores principales: Gill, Jonathan F., Delezie, Julien, Santos, Gesa, McGuirk, Shawn, Schnyder, Svenia, Frank, Stephan, Rausch, Martin, St‐Pierre, Julie, Handschin, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718523/
https://www.ncbi.nlm.nih.gov/pubmed/31290266
http://dx.doi.org/10.1111/acel.12993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718523/
https://www.ncbi.nlm.nih.gov/pubmed/31290266
http://dx.doi.org/10.1111/acel.12993

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