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Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90 + subset

Aging is a major risk factor in the development of chronic diseases, especially cardiovascular diseases. Age‐related organ dysfunction is strongly associated with the accumulation of senescent cells. Cardiac mesenchymal stromal cells (cMSCs), deemed part of the microenvironment, modulate cardiac hom...

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Detalles Bibliográficos
Autores principales: Martini, Hélène, Iacovoni, Jason S., Maggiorani, Damien, Dutaur, Marianne, Marsal, Dimitri J., Roncalli, Jerome, Itier, Romain, Dambrin, Camille, Pizzinat, Nathalie, Mialet‐Perez, Jeanne, Cussac, Daniel, Parini, Angelo, Lefevre, Lise, Douin‐Echinard, Victorine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718537/
https://www.ncbi.nlm.nih.gov/pubmed/31353772
http://dx.doi.org/10.1111/acel.13015