Neuronal‐specific proteasome augmentation via Prosβ5 overexpression extends lifespan and reduces age‐related cognitive decline

Cognitive function declines with age throughout the animal kingdom, and increasing evidence shows that disruption of the proteasome system contributes to this deterioration. The proteasome has important roles in multiple aspects of the nervous system, including synapse function and plasticity, as we...

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Detalles Bibliográficos
Autores principales: Munkácsy, Erin, Chocron, E. Sandra, Quintanilla, Laura, Gendron, Christi M., Pletcher, Scott D., Pickering, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Short Take
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718538/
https://www.ncbi.nlm.nih.gov/pubmed/31334599
http://dx.doi.org/10.1111/acel.13005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718538/
https://www.ncbi.nlm.nih.gov/pubmed/31334599
http://dx.doi.org/10.1111/acel.13005

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