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miR‐107 regulates growth and metastasis of gastric cancer cells via activation of the PI3K‐AKT signaling pathway by down‐regulating FAT4

PURPOSE: To investigate the effect of miR‐107 on the growth and metastasis of gastric cancer (GC) and elucidate the probable mechanisms. METHODS: The expression of miR‐107 and FAT4 in GC tissues and cells were detected using qRT‐PCR. Bioinformatics and dual luciferase reporter gene assays were used...

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Detalles Bibliográficos
Autores principales: Wang, Li, Li, Kunkun, Wang, Chen, Shi, Xiaoxin, Yang, Huiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718591/
https://www.ncbi.nlm.nih.gov/pubmed/31297980
http://dx.doi.org/10.1002/cam4.2396