Early‐onset aging and mitochondrial defects associated with loss of histone acetyltransferase 1 (Hat1)

Histone acetyltransferase 1 (Hat1) is responsible for the acetylation of newly synthesized histone H4 on lysines 5 and 12 during the process of chromatin assembly. To understand the broader biological role of Hat1, we have generated a conditional mouse knockout model of this enzyme. We previously re...

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Detalles Bibliográficos
Autores principales: Nagarajan, Prabakaran, Agudelo Garcia, Paula A., Iyer, Chitra C., Popova, Liudmila V., Arnold, William D., Parthun, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718594/
https://www.ncbi.nlm.nih.gov/pubmed/31290578
http://dx.doi.org/10.1111/acel.12992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718594/
https://www.ncbi.nlm.nih.gov/pubmed/31290578
http://dx.doi.org/10.1111/acel.12992

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