Oridonin induces Mdm2‐p60 to promote p53‐mediated apoptosis and cell cycle arrest in neuroblastoma

Oridonin could induce NB (neuroblastoma) cells growth inhibition by inducing apoptosis and cell cycle arrest, and the molecular mechanisms behind the effects deserve to be further explored. Here, oridonin was confirmed to cause the reactivation of p53 (cellular tumor antigen p53) to promote the expr...

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Detalles Bibliográficos
Autores principales: Zhu, Han‐Qing, Zhang, Chao, Guo, Zhu‐Ying, Yang, Jun‐Mei, Guo, Jia‐Hui, Chen, Chen, Yao, Qiang‐Hua, Liu, Feng, Zhang, Quan‐Wu, Gao, Feng‐Hou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718599/
https://www.ncbi.nlm.nih.gov/pubmed/31339234
http://dx.doi.org/10.1002/cam4.2393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718599/
https://www.ncbi.nlm.nih.gov/pubmed/31339234
http://dx.doi.org/10.1002/cam4.2393

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