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Oridonin induces Mdm2‐p60 to promote p53‐mediated apoptosis and cell cycle arrest in neuroblastoma
Oridonin could induce NB (neuroblastoma) cells growth inhibition by inducing apoptosis and cell cycle arrest, and the molecular mechanisms behind the effects deserve to be further explored. Here, oridonin was confirmed to cause the reactivation of p53 (cellular tumor antigen p53) to promote the expr...
Autores principales: | Zhu, Han‐Qing, Zhang, Chao, Guo, Zhu‐Ying, Yang, Jun‐Mei, Guo, Jia‐Hui, Chen, Chen, Yao, Qiang‐Hua, Liu, Feng, Zhang, Quan‐Wu, Gao, Feng‐Hou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718599/ https://www.ncbi.nlm.nih.gov/pubmed/31339234 http://dx.doi.org/10.1002/cam4.2393 |
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