Tumor-reprogrammed resident T cells resist radiation to control tumors

Successful combinations of radiotherapy and immunotherapy depend on the presence of live T cells within the tumor; however, radiotherapy is believed to damage T cells. Here, based on longitudinal in vivo imaging and functional analysis, we report that a large proportion of T cells survive clinically...

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Detalles Bibliográficos
Autores principales: Arina, Ainhoa, Beckett, Michael, Fernandez, Christian, Zheng, Wenxin, Pitroda, Sean, Chmura, Steven J., Luke, Jason J., Forde, Martin, Hou, Yuzhu, Burnette, Byron, Mauceri, Helena, Lowy, Israel, Sims, Tasha, Khodarev, Nikolai, Fu, Yang-Xin, Weichselbaum, Ralph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718618/
https://www.ncbi.nlm.nih.gov/pubmed/31477729
http://dx.doi.org/10.1038/s41467-019-11906-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718618/
https://www.ncbi.nlm.nih.gov/pubmed/31477729
http://dx.doi.org/10.1038/s41467-019-11906-2

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