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Tumor-reprogrammed resident T cells resist radiation to control tumors
Successful combinations of radiotherapy and immunotherapy depend on the presence of live T cells within the tumor; however, radiotherapy is believed to damage T cells. Here, based on longitudinal in vivo imaging and functional analysis, we report that a large proportion of T cells survive clinically...
Autores principales: | Arina, Ainhoa, Beckett, Michael, Fernandez, Christian, Zheng, Wenxin, Pitroda, Sean, Chmura, Steven J., Luke, Jason J., Forde, Martin, Hou, Yuzhu, Burnette, Byron, Mauceri, Helena, Lowy, Israel, Sims, Tasha, Khodarev, Nikolai, Fu, Yang-Xin, Weichselbaum, Ralph R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718618/ https://www.ncbi.nlm.nih.gov/pubmed/31477729 http://dx.doi.org/10.1038/s41467-019-11906-2 |
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