Two activating mutations of MPL in triple‐negative myeloproliferative neoplasms

MPLW515K or W515L mutation plays an important role in the pathogenesis of myeloproliferative neoplasms (MPNs) through signaling molecules of the cytokine receptor axis. Besides MPLW515K or W515L, more than 30 atypical MPL mutations have been reported in patients who are negative for JAK2V617F, MPLW5...

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Detalles Bibliográficos
Autores principales: Xie, Juan, Chen, Xiuhua, Gao, Feng, Hou, Ruixia, Tian, Tingting, Zhang, Yaofang, Fan, Lifang, Hu, Jinjun, Zhu, Guiyang, Yang, Wanfang, Wang, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718619/
https://www.ncbi.nlm.nih.gov/pubmed/31294534
http://dx.doi.org/10.1002/cam4.2387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718619/
https://www.ncbi.nlm.nih.gov/pubmed/31294534
http://dx.doi.org/10.1002/cam4.2387

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