Cochlear Glucocorticoid Receptor and Serum Corticosterone Expression in a Rodent Model of Noise-induced Hearing Loss: Comparison of Timing of Dexamethasone Administration

Glucocorticoid (GC) is a steroid hormone secreted from the adrenal cortex in response to stress, which acts by binding to cytoplasmic glucocorticoid receptors (GRs). Dexamethasone (DEX) is a synthetic GC exhibiting immunosuppressive effects in both human and rodent models of hearing loss. While clin...

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Detalles Bibliográficos
Autores principales: Lee, Seung-Hun, Lyu, Ah-Ra, Shin, Sun-Ae, Jeong, Seong-Hun, Lee, Sun-A, Park, Min Jung, Park, Yong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718671/
https://www.ncbi.nlm.nih.gov/pubmed/31477769
http://dx.doi.org/10.1038/s41598-019-49133-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718671/
https://www.ncbi.nlm.nih.gov/pubmed/31477769
http://dx.doi.org/10.1038/s41598-019-49133-w

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