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Sex-specific transcriptional and proteomic signatures in schizophrenia

It has remained unclear why schizophrenia typically manifests after adolescence and which neurobiological mechanisms are underlying the cascade leading to the actual onset of the illness. Here we show that the use of induced pluripotent stem cell-derived neurons of monozygotic twins from pairs disco...

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Detalles Bibliográficos
Autores principales: Tiihonen, Jari, Koskuvi, Marja, Storvik, Markus, Hyötyläinen, Ida, Gao, Yanyan, Puttonen, Katja A., Giniatullina, Raisa, Poguzhelskaya, Ekaterina, Ojansuu, Ilkka, Vaurio, Olli, Cannon, Tyrone D., Lönnqvist, Jouko, Therman, Sebastian, Suvisaari, Jaana, Kaprio, Jaakko, Cheng, Lesley, Hill, Andrew F., Lähteenvuo, Markku, Tohka, Jussi, Giniatullin, Rashid, Lehtonen, Šárka, Koistinaho, Jari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718673/
https://www.ncbi.nlm.nih.gov/pubmed/31477693
http://dx.doi.org/10.1038/s41467-019-11797-3