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An electrostatic switching mechanism to control the lipid transfer activity of Osh6p

A central assumption is that lipid transfer proteins (LTPs) bind transiently to organelle membranes to distribute lipids in the eukaryotic cell. Osh6p and Osh7p are yeast LTPs that transfer phosphatidylserine (PS) from the endoplasmic reticulum (ER) to the plasma membrane (PM) via PS/phosphatidylino...

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Detalles Bibliográficos
Autores principales: Lipp, Nicolas-Frédéric, Gautier, Romain, Magdeleine, Maud, Renard, Maxime, Albanèse, Véronique, Čopič, Alenka, Drin, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718676/
https://www.ncbi.nlm.nih.gov/pubmed/31477717
http://dx.doi.org/10.1038/s41467-019-11780-y