ITPA, TPMT, and NUDT15 Genetic Polymorphisms Predict 6-Mercaptopurine Toxicity in Middle Eastern Children With Acute Lymphoblastic Leukemia

Background: Acute lymphoblastic leukemia (ALL) is the most common cancer seen in children worldwide and in the Middle East. Although there have been major advances in treatment approaches for childhood ALL, serious toxicities do occur but with significant inter-individual variability. The aim of thi...

Descripción completa

Detalles Bibliográficos
Autores principales: Moradveisi, Borhan, Muwakkit, Samar, Zamani, Fatemeh, Ghaderi, Ebrahim, Mohammadi, Ebrahim, Zgheib, Nathalie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718715/
https://www.ncbi.nlm.nih.gov/pubmed/31507415
http://dx.doi.org/10.3389/fphar.2019.00916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718715/
https://www.ncbi.nlm.nih.gov/pubmed/31507415
http://dx.doi.org/10.3389/fphar.2019.00916

Ejemplares similares