A DNA-Based Biosensor Assay for the Kinetic Characterization of Ion-Dependent Aptamer Folding and Protein Binding

Therapeutic and diagnostic nucleic acid aptamers are designed to bind tightly and specifically to their target. The combination of structural and kinetic analyses of aptamer interactions has gained increasing importance. Here, we present a fluorescence-based switchSENSE aptasensor for the detailed k...

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Detalles Bibliográficos
Autores principales: Ponzo, Irene, Möller, Friederike M., Daub, Herwin, Matscheko, Nena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718989/
https://www.ncbi.nlm.nih.gov/pubmed/31398834
http://dx.doi.org/10.3390/molecules24162877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718989/
https://www.ncbi.nlm.nih.gov/pubmed/31398834
http://dx.doi.org/10.3390/molecules24162877

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