Involvement of Mitochondrial Dysfunction, Endoplasmic Reticulum Stress, and the PI3K/AKT/mTOR Pathway in Nobiletin-Induced Apoptosis of Human Bladder Cancer Cells

Nobiletin (NOB) is a polymethoxylated flavonoid isolated from citrus fruit peel that has been shown to possess anti-tumor, antithrombotic, antifungal, anti-inflammatory and anti-atherosclerotic activities. The main purpose of this study was to explore the potential of using NOB to induce apoptosis i...

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Detalles Bibliográficos
Autores principales: Goan, Yih-Gang, Wu, Wen-Tung, Liu, Chih-I, Neoh, Choo-Aun, Wu, Yu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719163/
https://www.ncbi.nlm.nih.gov/pubmed/31398899
http://dx.doi.org/10.3390/molecules24162881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719163/
https://www.ncbi.nlm.nih.gov/pubmed/31398899
http://dx.doi.org/10.3390/molecules24162881

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