Streptococcal Pyrogenic Exotoxin A-Stimulated Monocytes Mediate Regulatory T-Cell Accumulation through PD-L1 and Kynurenine

Bacterial superantigens (SAgs) are exotoxins that promote a fulminant activation of the immune system. The subsequent intense release of inflammatory cytokines often results in hypotension, shock, and organ failure with high mortality rates. In the current paradigm, the direct and simultaneous bindi...

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Detalles Bibliográficos
Autores principales: Giesbrecht, Katharina, Förmer, Sandra, Sähr, Aline, Heeg, Klaus, Hildebrand, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719222/
https://www.ncbi.nlm.nih.gov/pubmed/31412561
http://dx.doi.org/10.3390/ijms20163933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719222/
https://www.ncbi.nlm.nih.gov/pubmed/31412561
http://dx.doi.org/10.3390/ijms20163933

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