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Evaluation of the pharmacokinetics of metformin and acarbose in the common marmoset

Metformin has beneficial effects on several age-related diseases (e.g., diabetes, obesity, cancer) and extends lifespan in nematodes and mice. Acarbose, an FDA-approved agent for treating type 2 diabetes, prevents breakdown of complex carbohydrates. Both compounds have been suggested as potential an...

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Detalles Bibliográficos
Autores principales: Fernandez, Elizabeth, Ross, Corinna, Liang, Hanyu, Javors, Martin, Tardif, Suzette, Salmon, Adam B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719263/
https://www.ncbi.nlm.nih.gov/pubmed/31497263
http://dx.doi.org/10.1080/20010001.2019.1657756