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DNA analysis of low- and high-density fractions defines heterogeneous subpopulations of small extracellular vesicles based on their DNA cargo and topology

Extracellular vesicles have the capacity to transfer lipids, proteins, and nucleic acids between cells, thereby influencing the recipient cell’s phenotype. While the role of RNAs in EVs has been extensively studied, the function of DNA remains elusive. Here, we distinguished novel heterogeneous subp...

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Detalles Bibliográficos
Autores principales: Lázaro-Ibáñez, Elisa, Lässer, Cecilia, Shelke, Ganesh Vilas, Crescitelli, Rossella, Jang, Su Chul, Cvjetkovic, Aleksander, García-Rodríguez, Anaís, Lötvall, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719264/
https://www.ncbi.nlm.nih.gov/pubmed/31497265
http://dx.doi.org/10.1080/20013078.2019.1656993