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DNA analysis of low- and high-density fractions defines heterogeneous subpopulations of small extracellular vesicles based on their DNA cargo and topology
Extracellular vesicles have the capacity to transfer lipids, proteins, and nucleic acids between cells, thereby influencing the recipient cell’s phenotype. While the role of RNAs in EVs has been extensively studied, the function of DNA remains elusive. Here, we distinguished novel heterogeneous subp...
Autores principales: | Lázaro-Ibáñez, Elisa, Lässer, Cecilia, Shelke, Ganesh Vilas, Crescitelli, Rossella, Jang, Su Chul, Cvjetkovic, Aleksander, García-Rodríguez, Anaís, Lötvall, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719264/ https://www.ncbi.nlm.nih.gov/pubmed/31497265 http://dx.doi.org/10.1080/20013078.2019.1656993 |
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