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Effect of Oral Semaglutide on the Pharmacokinetics of Lisinopril, Warfarin, Digoxin, and Metformin in Healthy Subjects

BACKGROUND: Oral semaglutide is a tablet co-formulation of the human glucagon-like peptide-1 (GLP-1) analog semaglutide with the absorption enhancer sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC). The absorption of coadministered oral drugs may be altered due to enhancement by SNAC, potentia...

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Detalles Bibliográficos
Autores principales: Bækdal, Tine A., Borregaard, Jeanett, Hansen, Cilie W., Thomsen, Mette, Anderson, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719321/
https://www.ncbi.nlm.nih.gov/pubmed/30945118
http://dx.doi.org/10.1007/s40262-019-00756-2