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Effect of Oral Semaglutide on the Pharmacokinetics of Lisinopril, Warfarin, Digoxin, and Metformin in Healthy Subjects
BACKGROUND: Oral semaglutide is a tablet co-formulation of the human glucagon-like peptide-1 (GLP-1) analog semaglutide with the absorption enhancer sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC). The absorption of coadministered oral drugs may be altered due to enhancement by SNAC, potentia...
Autores principales: | Bækdal, Tine A., Borregaard, Jeanett, Hansen, Cilie W., Thomsen, Mette, Anderson, Thomas W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719321/ https://www.ncbi.nlm.nih.gov/pubmed/30945118 http://dx.doi.org/10.1007/s40262-019-00756-2 |
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