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Cardiac contractile dysfunction and protein kinase C–mediated myofilament phosphorylation in disease and aging

Increases in protein kinase C (PKC) are associated with diminished cardiac function, but the contribution of downstream myofilament phosphorylation is debated in human and animal models of heart failure. The current experiments evaluated PKC isoform expression, downstream cardiac troponin I (cTnI) S...

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Detalles Bibliográficos
Autores principales:	Ravichandran, Vani S., Patel, Himanshu J., Pagani, Francis D., Westfall, Margaret V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719401/ https://www.ncbi.nlm.nih.gov/pubmed/31366607 http://dx.doi.org/10.1085/jgp.201912353

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