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Triple arginines as molecular determinants for pentameric assembly of the intracellular domain of 5-HT(3A) receptors

Serotonin type 3 receptors (5-HT(3)Rs) are cation-conducting pentameric ligand-gated ion channels and members of the Cys-loop superfamily in eukaryotes. 5-HT(3)Rs are found in the peripheral and central nervous system, and they are targets for drugs used to treat anxiety, drug dependence, and schizo...

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Detalles Bibliográficos
Autores principales: Pandhare, Akash, Pirayesh, Elham, Stuebler, Antonia G., Jansen, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719409/
https://www.ncbi.nlm.nih.gov/pubmed/31409663
http://dx.doi.org/10.1085/jgp.201912421