Cargando…

Triple arginines as molecular determinants for pentameric assembly of the intracellular domain of 5-HT(3A) receptors

Serotonin type 3 receptors (5-HT(3)Rs) are cation-conducting pentameric ligand-gated ion channels and members of the Cys-loop superfamily in eukaryotes. 5-HT(3)Rs are found in the peripheral and central nervous system, and they are targets for drugs used to treat anxiety, drug dependence, and schizo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pandhare, Akash, Pirayesh, Elham, Stuebler, Antonia G., Jansen, Michaela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719409/ https://www.ncbi.nlm.nih.gov/pubmed/31409663 http://dx.doi.org/10.1085/jgp.201912421

Ejemplares similares

Pentameric quaternary structure of the intracellular domain of serotonin type 3A receptors
por: Pandhare, Akash, et al.
Publicado: (2016)

Mobility of Lower MA-Helices for Ion Conduction through Lateral Portals in 5-HT(3A) Receptors
por: Stuebler, Antonia G., et al.
Publicado: (2020)

Identification of a binding site for bupropion in Gloeobacter violaceus ligand-gated ion channel
por: Pirayesh, Elham, et al.
Publicado: (2023)

Pentameric assembly of the Kv2.1 tetramerization domain
por: Xu, Zhen, et al.
Publicado: (2022)

Bupropion Inhibits Serotonin Type 3AB Heteromeric Channels at Clinically Relevant Concentrations
por: Stuebler, Antonia G., et al.
Publicado: (2020)

Probing the Dynamics of the Imine-Based Pentafoil Knot and Pentameric Circular Helicate Assembly
por: Ayme, Jean-François, et al.
Publicado: (2019)

Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels
por: Bertozzi, Carlo, et al.
Publicado: (2016)

Correction: Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels
Publicado: (2016)

Hetero-pentamerization determines mobility and conductance of Glycine receptor α3 splice variants
por: Lemmens, Veerle, et al.
Publicado: (2022)

Pentameric ligand-gated ion channels exhibit distinct transmembrane domain archetypes for folding/expression and function
por: Therien, J. P. Daniel, et al.
Publicado: (2017)

MERS coronavirus envelope protein has a single transmembrane domain that forms pentameric ion channels
por: Surya, Wahyu, et al.
Publicado: (2015)

Biophysical characterization of calcium-binding and modulatory-domain dynamics in a pentameric ligand-gated ion channel
por: Lycksell, Marie, et al.
Publicado: (2022)

Impact of intracellular domain flexibility upon properties of activated human 5-HT(3) receptors*
por: Kozuska, J L, et al.
Publicado: (2014)

The Pentameric Channel of COMPcc in Complex with Different Fatty Acids
por: MacFarlane, Ainsley A., et al.
Publicado: (2012)

Protein dynamics and the allosteric transitions of pentameric receptor channels
por: Changeux, Jean-Pierre
Publicado: (2014)

Bacterial resistance in India: Studying plasma antibiotic levels
por: Pandhare, Akash
Publicado: (2015)

Tyrosine Side‐Chain Functionalities at Distinct Positions Determine the Chirooptical Properties and Supramolecular Structures of Pentameric Oligothiophenes
por: Bäck, Marcus, et al.
Publicado: (2020)

A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers
por: Llauger, Gabriela, et al.
Publicado: (2023)

Production of Pentameric Cholera Toxin B Subunit in Escherichia coli
por: Dakterzada, Farida, et al.
Publicado: (2012)

Recognition Functions of Pentameric C-Reactive Protein in Cardiovascular Disease
por: Agrawal, Alok, et al.
Publicado: (2014)

Signal Transduction Pathways in the Pentameric Ligand-Gated Ion Channels
por: Mowrey, David, et al.
Publicado: (2013)

Early Cambrian Pentamerous Cubozoan Embryos from South China
por: Han, Jian, et al.
Publicado: (2013)

Correction: The Pentameric Channel of COMPcc in Complex with Different Fatty Acids
por: McFarlane, Ainsley, et al.
Publicado: (2013)

Hexameric and pentameric complexes of the ExbBD energizer in the Ton system
por: Maki-Yonekura, Saori, et al.
Publicado: (2018)

Effect of pressure on refolding of recombinant pentameric cholera toxin B
por: Rodrigues, D., et al.
Publicado: (2014)

Asymmetric gating of a human hetero-pentameric glycine receptor
por: Liu, Xiaofen, et al.
Publicado: (2023)

Phospholamban pentamerization increases sensitivity and dynamic range of cardiac relaxation
por: Funk, Florian, et al.
Publicado: (2023)

Asymmetric gating of a human hetero-pentameric glycine receptor
por: Liu, Xiaofen, et al.
Publicado: (2023)

Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels
por: Lynagh, Timothy, et al.
Publicado: (2015)

Molecular Mingling: Multimodal Predictions of Ligand Promiscuity in Pentameric Ligand-Gated Ion Channels
por: Koniuszewski, Filip, et al.
Publicado: (2022)

Cryo-electron microscopic and X-ray crystallographic analysis of the light-driven proton pump proteorhodopsin reveals a pentameric assembly
por: Hirschi, Stephan, et al.
Publicado: (2020)

Structural Flexibility of the Pentameric SARS Coronavirus Envelope Protein Ion Channel
por: Parthasarathy, Krupakar, et al.
Publicado: (2008)

Ligand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC
por: Zimmermann, Iwan, et al.
Publicado: (2011)

Evolution of Pentameric Ligand-Gated Ion Channels: Pro-Loop Receptors
por: Jaiteh, Mariama, et al.
Publicado: (2016)

Chasing the open-state structure of pentameric ligand-gated ion channels
por: Gonzalez-Gutierrez, Giovanni, et al.
Publicado: (2017)

Correction: Hexameric and pentameric complexes of the ExbBD energizer in the Ton system
por: Yonekura, Koji, et al.
Publicado: (2018)

Identification of a pre-active conformation of a pentameric channel receptor
por: Menny, Anaïs, et al.
Publicado: (2017)

A pentameric protein ring with novel architecture is required for herpesviral packaging
por: Didychuk, Allison L, et al.
Publicado: (2021)

Molecular Simulations of Hydrophobic Gating of Pentameric Ligand Gated Ion Channels: Insights into Water and Ions
por: Rao, Shanlin, et al.
Publicado: (2021)

Opposing effects of monomeric and pentameric C-reactive protein on endothelial progenitor cells
por: Ahrens, I., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_gb6j93348dk82i1ak5gh50i0s5