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The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses

T helper 17 cells (Th17) are critical for fighting infections at mucosal surfaces; however, they have also been found to contribute to the pathogenesis of multiple autoimmune diseases and have been targeted therapeutically. Due to the role of Th17 cells in autoimmune pathogenesis, it is important to...

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Detalles Bibliográficos
Autores principales: Sin, Jun Hyung, Zuckerman, Cassandra, Cortez, Jessica T., Eckalbar, Walter L., Erle, David J., Anderson, Mark S., Waterfield, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719416/
https://www.ncbi.nlm.nih.gov/pubmed/31217192
http://dx.doi.org/10.1084/jem.20182316