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The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses
T helper 17 cells (Th17) are critical for fighting infections at mucosal surfaces; however, they have also been found to contribute to the pathogenesis of multiple autoimmune diseases and have been targeted therapeutically. Due to the role of Th17 cells in autoimmune pathogenesis, it is important to...
Autores principales: | Sin, Jun Hyung, Zuckerman, Cassandra, Cortez, Jessica T., Eckalbar, Walter L., Erle, David J., Anderson, Mark S., Waterfield, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719416/ https://www.ncbi.nlm.nih.gov/pubmed/31217192 http://dx.doi.org/10.1084/jem.20182316 |
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