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Caveolin-1 selectively regulates microRNA sorting into microvesicles after noxious stimuli

Emerging evidence suggests that extracellular vesicle (EV)–containing miRNAs mediate intercellular communications in response to noxious stimuli. It remains unclear how a cell selectively sorts the cellular miRNAs into EVs. We report that caveolin-1 (cav-1) is essential for sorting of selected miRNA...

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Detalles Bibliográficos
Autores principales: Lee, Heedoo, Li, Chunhua, Zhang, Yang, Zhang, Duo, Otterbein, Leo E., Jin, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719430/
https://www.ncbi.nlm.nih.gov/pubmed/31235510
http://dx.doi.org/10.1084/jem.20182313