Cargando…

Chromatin targeting of nuclear pore proteins induces chromatin decondensation

Nuclear pore complexes have emerged in recent years as chromatin-binding nuclear scaffolds, able to influence target gene expression. However, how nucleoporins (Nups) exert this control remains poorly understood. Here we show that ectopically tethering Drosophila Nups, especially Sec13, to chromatin...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuhn, Terra M., Pascual-Garcia, Pau, Gozalo, Alejandro, Little, Shawn C., Capelson, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719443/
https://www.ncbi.nlm.nih.gov/pubmed/31366666
http://dx.doi.org/10.1083/jcb.201807139