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Challenging the “chromatin hypothesis” of cardiac laminopathies with LMNA mutant iPS cells
Lamins A and C are intermediate filaments that provide structural support to the nuclear envelope and regulate gene expression. In this issue, Bertero et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201902117) report that although lamin A/C haploinsufficient cardiomyocytes show disease-assoc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719444/ https://www.ncbi.nlm.nih.gov/pubmed/31427369 http://dx.doi.org/10.1083/jcb.201907166 |