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A bipartite sorting signal ensures specificity of retromer complex in membrane protein recycling

Retromer is an evolutionarily conserved protein complex, which sorts functionally diverse membrane proteins into recycling tubules/vesicles from the endosome. Many of the identified cargos possess a recycling signal sequence defined as ØX[L/M/V], where Ø is F/Y/W. However, this sequence is present i...

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Detalles Bibliográficos
Autores principales: Suzuki, Sho W., Chuang, Ya-Shan, Li, Ming, Seaman, Matthew N.J., Emr, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719449/
https://www.ncbi.nlm.nih.gov/pubmed/31337624
http://dx.doi.org/10.1083/jcb.201901019