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Direct observation of branching MT nucleation in living animal cells

Centrosome-mediated microtubule (MT) nucleation has been well characterized; however, numerous noncentrosomal MT nucleation mechanisms exist. The branching MT nucleation pathway envisages that the γ-tubulin ring complex (γ-TuRC) is recruited to MTs by the augmin complex to initiate nucleation of new...

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Detalles Bibliográficos
Autores principales: Verma, Vikash, Maresca, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719462/
https://www.ncbi.nlm.nih.gov/pubmed/31340987
http://dx.doi.org/10.1083/jcb.201904114