Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA

Amino acid starvation in Escherichia coli activates the enzymatic activity of the stringent factor RelA, leading to accumulation of the alarmone nucleotide (p)ppGpp. The alarmone acts as an intercellular messenger to regulate transcription, translation and metabolism to mediate bacterial stress adap...

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Detalles Bibliográficos
Autores principales: Turnbull, Kathryn Jane, Dzhygyr, Ievgen, Lindemose, Søren, Hauryliuk, Vasili, Roghanian, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719525/
https://www.ncbi.nlm.nih.gov/pubmed/31507571
http://dx.doi.org/10.3389/fmicb.2019.01966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719525/
https://www.ncbi.nlm.nih.gov/pubmed/31507571
http://dx.doi.org/10.3389/fmicb.2019.01966

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