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Redox-Responsive Disulfide Bond-Bridged mPEG-PBLA Prodrug Micelles for Enhanced Paclitaxel Biosafety and Antitumor Efficacy

The toxicity and side effects of traditional chemotherapeutic drugs are the main causes of chemotherapy failure. To improve the specificity and selectivity of chemotherapeutic drugs for tumor cells, a novel redox-sensitive polymer prodrug, polyethylene glycol-poly (β-benzyl-L-aspartate) (PEG-PBLA)-S...

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Detalles Bibliográficos
Autores principales: Chang, Sheng, Wang, Yanfei, Zhang, Tianyi, Pu, Xiaohui, Zong, Lanlan, Zhu, Heyun, Zhao, Luling, Feng, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719549/
https://www.ncbi.nlm.nih.gov/pubmed/31508374
http://dx.doi.org/10.3389/fonc.2019.00823