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Brilliant Blue G Inhibits Inflammasome Activation and Reduces Disruption of Blood–Spinal Cord Barrier Induced by Spinal Cord Injury in Rats

BACKGROUND: Brilliant blue G (BBG) is a P2X7 receptor inhibitor that has been reported to improve spinal cord injury (SCI) in previous studies, but the specific mechanism has been unclear. In this study, we investigated the effects of BBG on inflammasomes and blood–spinal cord barrier (BSCB) permeab...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Yang, Yan, Wu, Liying, Wang, Yiding, Du, Chenyang, Li, Chenxu, Wang, Zihao, Wang, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719612/
https://www.ncbi.nlm.nih.gov/pubmed/31444877
http://dx.doi.org/10.12659/MSM.915865